Funded Projects

Anton Aebischer (2011-2017)

Functional analysis of molecular components of the habitat of Leishmania spp. – the protozoan parasites causing human leishmaniases

Ivan Dikic (2014-2017)

Protein networks in the biogenesis of the proliferative niche of Salmonella

Antje Flieger (2011-2017)

Significance of Legionella pneumophila phospholipases for modification of lipids within the phagosomal membrane

Gareth Griffiths (2011-2017)

State of the art ultra-structural analysis of pathogen-containing compartments.

Maximiliano Gutierrez (2011-2014)

Analysis of the function and regulation of Rab20 during mycobacterial phagosome maturation

Thomas Gutsmann (2011-2014)

Structural and biophysical characterization of the interaction between intracellular pathogens and phagosome membranes (joint project with PD Dr. Buko Lindner)

Albert Haas (2011-2017)

(joint project with Paul Saftig) Lysosomal Membrane Proteins and their Roles in Phagosome Maturation

Georg Häcker (2011-2017)

Establishment and maintenance of the chlamydial inclusion: requirement for septins and the inhibition of host cell translation

Monica Hagedorn (2014-2017)

Investigation of Francisella virulence and host cell defense mechanisms in Dictyostelium

Kirsten Heiss (2014-2017)

Malaria intrahepatic interactions and trafficking: Deciphering the molecular machinery driving vesicular trafficking and membrane fusion between the hepatic host environment and malarial parasite for parasitophorous vacular membrane dynamics (project together with Ann-Kristin Mueller)

Ilka Haferkamp (2011-2014)

Solute provision to the chlamydial inclusion

Michael Hensel (2011-2017)

Biogenesis of novel membrane compartments in Salmonella enterica-infected host cells

Dagmar Heuer (2011-2017)

Chlamydia interacts with the Golgi apparatus – understanding the underlying molecular mechanisms

Hubert Hilbi (2011-2014)

Functional phosphoinositide lipidomics of Legionella-containing vacuoles

Mathias Hornef (2014-2017)

In vivo Formation and Maintenance of Salmonella-Containing Vacuoles (SCVs) in Enterocytes using a Novel Neonatal Mouse Model

Bernhard Hube (2011-2017)

Survival and proliferation of human pathogenic Candida species within phagocytes

Alyssa Ingmundson (2011-2014)

Characterizing Plasmodium proteins at the host-pathogen vacuolar interface during parasite development in the liver

Michael R. Knittler (2014-2017)

Impact of the cytoprotective chaperone HSP25/27 on the structural integrity and autophagic degradation of chlamydial compartments

Buko Lindner (2011-2014)

Structural and biophysical characterization of the interaction between intracellular pathogens and phagosome membranes (joint project with Prof. Dr. Thomas Gutsmann)

Klaus Lingelbach (2011-2014)

Mechanisms underlying parasite induced permeability changes of the human erythrocyte membrane - how much is host, how much is parasite?

Anja Lührmann (2011-2017)

Trafficking der Coxiella burnetii-enthaltenden Vakuole

Ann-Kristin Müller (2011-2017)

Malaria intrahepatic interactions and trafficking: Deciphering the molecular machinery driving vesicular trafficking and membrane fusion between the hepatic host environment and malarial parasite for parasitophorous vacular membrane dynamics (joint project with Dr. Kirsten Heiß)

Bastian Opitz (2014-2017)

IFN-dependent macrophage-intrinsic innate resistance to Legionella pneumophila

Gabriele Pradel (2011-2017)

The egress of malaria gametocytes from the red blood cell following parasite transmission to the mosquito

Gerrit Praefcke (2011-2014)

The role of the human guanylate-binding protein 1 in the formation and trafficking of phagosomes and other pathogen containing membrane compartments

Jude Marek Przyborski (2011-2017)

Exported Plasmodium falciparum chaperones and co-chaperones: Relevance for intra-erythrocytic parasite survival

Norbert Reiling (2011-2017)

Clade specific virulence patterns of M. tuberculosis complex strains in human macrophages: Molecular mechanisms underlying phagosomal escape and induction of cell death (joint project with Prof. Dr. Stefan Schütze)

Thomas Rudel (2011-2017)

Formation and transport of Simkania negevensis vacuole and modulation of host cell signal transduction

Paul Saftig (2011-2017)

Lysosomal Membrane Proteins and their Roles in Phagosome Maturation (joint project with Prof. Dr. Albert Haas)

Ulrich E. Schaible (2011-2017)

The phagosomal fate of Mycobacterium tuberculosis-infected dying/dead cells

Stefan Schütze (2011-2017)

Clade specific virulence patterns of M. tuberculosis complex strains in human macrophages: Molecular mechanisms underlying phagosomal escape and induction of cell death (joint project with Norbert Reiling)

Tobias Spielmann (2014-2017)

Characterisation of the vacuolar compartment of malaria parasites within human red blood cells

Stefan Tenzer (2014-2017)

Functional characterization of cell-specific differences of L. major-containing phagolysosomes in macrophages and dendritic cells (joint project with Esther von Stebut-Borschitz)

Esther von Stebut-Borschitz (2014-2017)

Functional characterization of cell-specific differences of L. major-containing phagolysosomes in macrophages and dendritic cells (joint project with Stefan Tenzer)

Ger van Zandbergen (2011-2017)

Leishmania major promastigote entry of the of the autophagic compartment and amastigote escape from the parasitophorous vacuole (joint project with Prof. Dr. Paul Walther)

Paul Walther (2011-2017)

Leishmania major promastigote entry of the of the autophagic compartment and amastigote escape from the parasitophorous vacuole (joint project with Dr. Ger van Zandbergen)