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Publications from the SPP 1580

Principal Investigators of the SPP 1580 are printed in bold


In addition to all references below, we refer to the Special January 2018 Issue on “Intracellular Compartments as Places of Pathogen-Host Interaction” of the International Journal of Microbiology to which the members of SPP 1580 have contributed 26 papers:

Aeberhard, L., Banhart, S., Fischer, M., Jehmlich, N., Rose, L., Koch, S., Laue, M., Renard, B.Y., Schmidt, F., Heuer, D. (2015) The Proteome of the isolated Chlamydia trachomatis containing vacuole reveals a complex trafficking platform enriched for retromer components. PLoS Pathog. 11: e1004883

Aebischer, T. (2014) The Leishmania spp. proteome data sets: A comprehensive resource for vaccine development to target visceral leishmaniasis. Front Immunol 5: 260

Ahrendt, T., Miltenberger, M., Haneburger, I., Kirchner, F., Brachmann, A.O., Kronenwerth, M., Hilbi, H., Bode, H.B. (2013) Biosynthesis of the natural fluorophore legioliulin from Legionella. Chembiochem 14: 1415-1418

Aurass, P., Schlegel, M., Metwally, O., Harding, C. R., Schroeder, G. N., Frankel, G., Flieger, A. (2013) The Legionella pneumophila Dot/Icm-secreted effector PlcC/CegC1 together with PlcA and PlcB promotes virulence and belongs to a novel zinc metallophospholipase C family present in bacteria and fungi. J Biol Chem 288: 11080-11092

Banhart, S., Saied, E.M., Martini, A., Koch, S., Aeberhard, L., Madela, K., Arenz, C., Heuer, D. (2014) Improved Plaque Assay Identifies a Novel Anti-Chlamydia Ceramide Derivative with Altered Intracellular Localization. Antimicrob Agents Chemother 58: 5537-5546

Bargieri, D.Y., Thiberge, S., Tay, C.L., Carey, A.F., Rantz, A., Hischen, F., Lorthiois, A., Straschil, U., Singh, P., Singh, S., Triglia, T., Tsuboi, T., Cowman, A., Chitnis, C., Alano, P.,  Baum, J., Pradel, G., Lavazec, C., Menard, R. (2016) Plasmodium Merozoite TRAP Family Protein Is Essential for Vacuole Membrane Disruption and Gamete Egress from Erythrocytes. Cell Host Microbe 20: 618-630

Baumeister S, Gangopadhyay P, Repnik U, Lingelbach K. (2015) Novel insights into red blood cell physiology using parasites as tools. Eur J Cell Biol 94: 33233-33239.

Bayer, C., Varani, S., Wang, L., Walther, P., Zhou, S., Straschewski, S., Bachem, M., Söderberg-Naucler, C., Mertens, T., Frascaroli, G. (2013) Human cytomegalovirus infection of M1 and M2 macrophages triggers inflammation and autologous T-cell proliferation. J Virol 87: 67-79

Bayer C, Varani S, Wang L, Walther P, Zhou S, Straschewski S, Bachem M, Söderberg-Naucler C, Mertens T, Frascaroli G. (2013) Human cytomegalovirus infection of M1 and M2 macrophages triggers inflammation and autologous T-cell proliferation. J Virol 87: 67-79

Bennink, S., Kiesow, M.J., Pradel, G. (2016) The development of malaria parasites in the mosquito midgut. Cell Microbiol 18: 905-918

Bennink S, von Bohl A, Ngwa CJ, Henschel L, Kuehn A, Pilch N, Weißbach T, Rosinski AN, Scheuermayer M, Repnik U, Przyborski JM, Minns AM, Orchard LM, Griffiths G, Lindner SE, Llinás M, Pradel G. (2018) A seven-helix protein constitutes stress granules crucial for regulating translation during human-to-mosquito transmission of Plasmodium falciparum. PLoS Pathog 14:e1007249

Bhabak, K.P., Hauser, A., Redmer, S., Banhart, S., Heuer, D., Arenz, C. (2013) Development of a Novel FRET Probe for the Real-Time Determination of Ceramidase Activity. ChembioChem 14: 1049-1052

Biniossek, M.L., Niemer, M., Maksimchuk, K., Mayer, B., Fuchs, J., Huesgen, P.F., McCafferty, D.G., Turk, B., Fritz, G., Mayer, J., Häcker, G., Mach, L., Schilling, O. (2016) Identification of Protease Specificity by Combining Proteome-Derived Peptide Libraries and Quantitative Proteomics. Mol Cell Proteom 15: 2515 - 2524

Brenz Y, Ohnezeit D, Winther-Larsen H, Hagedorn M. (2017) Nramp1 and NrampB contribute to resistance against Francisella in Dictyostelium, Front Microbiol 7: 282

Bronietzki, M., Gutierrez, M.G.  (2014) Study of Phagolysosome Biogenesis in Live Macrophages, J Vis Exp, 85, doi: 10.3791/51201

Brunke, S., Hube, B. (2013) Two unlike cousins: Candida albicans and C. glabrata infection strategies. Cell Microbiol 15: 701-708

Brunke, S., Seider, K., Fischer, D., Jacobsen, I.D., Kasper, L., Jablonowski, N., Wartenberg, A., Bader, O., Enache-Angoulvant, A., Schaller, M., d‘Enfert, C., Hube, B. (2014) One Small Step for a Yeast - Microevolution within Macrophages Renders Candida glabrata Hypervirulent Due to a Single Point Mutation. PLoS Pathog. 10: e1004478

Chowdhury, S.R., Rudel, T. (2017) Chlamydia and mitochondria – an unfragmented relationship. Microbial Cell 4: 233-235

Chowdhury, S.R., Reimer, A., Sharan, M., Kozjak-Pavlovic, V., Eulalio, A., Prusty, B.K., Fraunholz, M., Karunakaran, K., Rudel, T. (2017) Chlamydia preserves the mitochondrial network necessary for replication via microRNA-dependent inhibition of fission. J Cell Biol 216: 1071-1089

Crauwels, P., Bohn, R., Thomas, M., Gottwalt, S., Jäckel, F., Krämer, S., Bank, E., Tenzer, S., Walther, P., Bastian, M., van Zandbergen, G. (2015). Apoptotic-like Leishmania exploit the host's autophagy machinery to reduce T-cell-mediated parasite elimination. Autophagy 11: 285-297

Dallenga, T., Corleis, B., Schaible, U.E. (2015) Infection of Human Neutrophils to Study Virulence Properties of Mycobacterium tuberculosis. Meth Mol Biol 1285: 343-355

Dallenga, T., Schaible, U.E. (2016) Neutrophils in tuberculosis--first line of defence or booster of disease and targets for host-directed therapy? Pathog Dis 74, pii: ftw012

Dallenga, T., Repnik, U., Corleis, B., Eich, J., Reimer, R., Griffiths, G.W., Schaible, U.E. (2017) M. tuberculosis-Induced Necrosis of Infected Neutrophils Promotes Bacterial Growth Following Phagocytosis by Macrophages. Cell Host Microbe 22: 519-530

Deligianni, E., Morgan, R.N., Bertuccini, L., Wirth, C.C., Silmon de Monerri, N.C., Spanos, L., Blackman, M.J., Louis, C., Pradel, G., Siden-Kiamos, I. (2013) A perforin-like protein mediates disruption of the erythrocyte mebrane during egress of Plasmodium berghei male gametocytes. Cell Microbiol 15: 1438-1455

Dille, S., Herbst, K., Volceanov, L., Nölke, T., Kretz, O., Häcker, G.  (2014) Golgi Fragmentation and Sphingomyelin Transport to Chlamydia trachomatis during Penicillin-Induced Persistence Do Not depend on the cytosolic presence of the chlamydial protease CPAF.  PLoS One 9: e103220

Dille, S., Kleinschnitz, E.M., Kontchou, C.W., Nölke, T., Häcker, G.  (2015) In Contrast to Chlamydia trachomatis, Waddlia chondrophila Grows in Human Cells without Inhibiting Apoptosis, Fragmenting the Golgi Apparatus, or Diverting Post-Golgi Sphingomyelin Transport. Infect Immun 83: 3268-3280

Dolinsky, S., Haneburger, I., Cichy, A., Hannemann, M., Itzen, A., Hilbi, H. (2014) The Legionella longbeachae Icm/Dot Substrate SidC Selectively Binds Phosphatidylinositol 4-Phosphate with Nanomolar Affinity and Promotes Pathogen Vacuole-Endoplasmic Reticulum Interactions. Infect Immun 82: 4021-4033

Dupont, A., Sommer, F., Zhang, K., Repnik, U., Basic, M., Bleich, A., Kühnel, M., Bäckhed, F., Litvak, Y., Fulde, M., Rosenshine, I., Hornef, M.W. (2016) Age-Dependent Susceptibility to Enteropathogenic Escherichia coli (EPEC) Infection in Mice. PLoS Pathog. 12: e1005616

Eckart, R.A.,  Bisle, S., Schulze-Luehrmann, J., Wittmann, I., Jantsch, J., Schmid, B., Berens, C., Lührmann, A. (2014) The anti-apoptotic activity of the Coxiella burnetii effector protein AnkG is controlled by p32-dependent trafficking. Infect Immun 82: 2763 - 2771

Finsel, I., Hoffmann, C., Hilbi, H. (2013) Immunomagnetic purification of fluorescent Legionella -containing vacuoles. Dictyostelium discoideum Protocols, Meth Mol Biol 983: 431-443

Finsel, I., Ragaz, C., Hoffmann, C., Harrison, C.F., Weber, S., van Rahden, V.A., Johannes, L., Hilbi, H. (2013) The Legionella Effector RidL Inhibits Retrograde Trafficking to Promote Intracellular Replication. Cell Host & Microbe 14: 38–50

Fischer, A., Harrison, K.S., Ramirez, Y., Auer, D., Chowdhury, S.R., Prusty, B.K., Sauer, F., Dimond, Z., Kisker, C., Hefty, P.S., Rudel, T. (2017) Chlamydia trachomatis-containing vacuole serves as deubiquitination platform to stabilize Mcl-1 and to interfere with host defense. Elife 6. pii: e21465

Fiskin, E., Bhogaraju S., Herhaus, L., Kalayil, S., Hahn, M., Dikic, I. (2017) Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA. Nature Commun 8: 14004

Flieger, A., Frischknecht, F., Häcker, G., Hornef, M.W., Pradel, G. (2018) Pathways of host cell exit by intracellular pathogens. Microbial Cell 5: 525-544

Friedrich, A., Pechstein, J., Berens, C., Lührmann, A. (2017) Modulation of host cell apoptotic pathways by intracellular pathogens. Curr Opin Microbiol 35: 88-99

Fulde, M., Sommer, F., Chassaing, B., van Vorst, K., Dupont, A., Hensel, M., Basic, M., Klopfleisch, R., Rosenstiel, P., Bleich, A., Bäckhed, F., Gewirtz, A.T., Hornef, M.W. (2018) Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition. Nature 560: 489-493

Gazdag, E.M., Streller, A., Haneburger, I., Hilbi, H., Vetter, I.R., Goody, R.S., Itzen, A. (2013) Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB. EMBO Rep 14: 199-205

Gerwien, F., Safyan, A., Wisgott, S., Hille, F., Kaemmer, P., Linde, J., Brunke, S., Kasper, L., Hube, B. (2016) A Novel Hybrid Iron Regulation Network Combines Features from Pathogenic and Nonpathogenic Yeasts. MBio  7: e01782-16

Gow, N,A, Hube, B. (2012) Importance of the Candida albicans cell wall during commensalism and infection. Curr Opin Microbiol 15: 406-412

Grimm, C., Holdt, L.M., Chen, C.C., Hassan, S., Müller, C., Jörs, S., Cuny, H., Kissing, S., Schröder, B., Butz, E., Northoff, B., Castonguay, J., Luber, C.A., Moser, M., Spahn, S., Lüllmann-Rauch, R., Fendel, C., Klugbauer, N., Griesbeck, O., Haas, A., Mann, M., Bracher, F., Teupser, D., Saftig, P., Biel, M., Wahl-Schott, C. (2014) High susceptibility to fatty liver disease in two.pore channel 2-deficient mice. Nature Commun 5: 4699

Grützke, J., Rindte, K., Goosmann, C., Silvie, O., Rauch, C., Heuer, D., Lehmann, M.J., Mueller, A.K., Brinkmann, V., Matuschewski, K., Ingmundson, A. (2014) The spatiotemporal dynamics and membranous features of the Plasmodium liver stage tubovesicular network. Traffic 15: 362-382

Gutierrez, M.G. (2013) Functional role(s) of phagosomal Rab GTPases. Small GTPases 4: 148-158

Haas, A., Jeschke, A. (2016) Deciphering the roles of phosphoinositide lipids in phagolysosome biogenesis. Commun Integr Biol 9: e1174798

Haferkamp, I., Penz, T., Geier, M., Ast, M., Mushak, T., Horn, M., Schmitz-Esser, S. (2013) The endosymbiont Amoebophilus asiaticus encodes an S-adenosylmethionine carrier that compensates for its missing methylation cycle. J Bacteriol 195: 3183-3192

Haneburger, I., Hilbi, H. (2013) Phosphoinositides and the Legionella pathogen vacuole. In: Curr Top Microbiol Immunol 376. Molecular mechanisms in Legionella pathogenesis. Hilbi, H. (ed.), Wiley Press; pp. 155-173

Harrison, C.F., Chiriano, G., Finsel, I., Manske, C., Hoffmann, C., Steiner, B., Kranjc, A., Patthey-Vuadens, O., Kicka, S., Trofimov, V., Ouertatani-Sakouhi, H., Soldati, T., Scapozza L., Hilbi, H. (2015) Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophila. ACS Infect Dis 1: 327-338

Harrison, C.F., Kicka, S., Kranjc, A., Finsel, I., Chiriano, G., Ouertatani-Sakouhi, H., Soldati, T., Scapozza, L., Hilbi, H. (2015) Adrenergic antagonists restrict replication of Legionella. Microbiol 161: 1392-1406

Harrison, C.F., Hilbi, H. (2016) Identification of anti-infective compounds using amoebae. In: Host - pathogen interaction: microbial metabolism, pathogenicity and anti-infectives. Unden, G. Thines, E. & Schüffler, A. (eds). Wiley-Blackwell Press; pp. 139-152

Hentzschel, F., Herrmann, A.K., A.K. Mueller, Grimm, D. (2016) Plasmodium meets AAV – the (un)likely marriage of parasitology and virology, and how to make the match. FEBS Lett 590: 2027-2045

Herweg, J.A., Hansmeier, N., Otto, A., Geffken, A.C., Subbarayal, P., Prusty, B.K., Becher, D., Hensel, M., Schaible, U.E., Rudel, T., Hilbi, H. (2015) Purification and proteomics of pathogen-modified vacuoles and membranes. Front Cell Infect Microbiol  5: 48

Herweg, J.A., Pons, V., Becher, D., Hecker, M., Krohne, G., Barbier, J., Berger, H., Rudel, T., Mehlitz, A. (2016) Proteomic analysis of the Simkania-containing vacuole: the central role of retrograde transport. Mol Microbiol 9:151-71

Herweg, J.A., Rudel, T. (2016) Interaction of Chlamydiae with human macrophages. FEBS J 283: 608-618

Hilbi, H., Haas, A. (2012). Secretive bacterial pathogens and the secretory pathway. Traffic 13: 1187-1197

Hilbi, H., Kortholt, A. (2017) Role of the small GTPase Rap1 in signal transduction, cell dynamics and bacterial infection. Small GTPases: doi: 10.1080/21541248.2017.1331721.

Hoffmann, C., Finsel, I., Hilbi, H. (2012) Purification of Pathogen Vacuoles from Legionella-Infected Phagocytes. Video Article. J Vis Exp  64, e4118

Hoffmann, C., Finsel, I., Hilbi, H. (2013). Pathogen Vacuole Purification from Legionella -Infected Amoeba and Macrophages. Meth Mol Biol 954: 309-321

Hoffmann, C., Finsel, I., Otto, A., Pfaffinger, G., Rothmeier, E., Hecker, M., Becher, D., Hilbi, H. (2014) Functional analysis of novel small GTPases identified in the proteome of purified Legionella-containing vacuoles from macrophages. Cell Microbiol 16: 1034-1052

Hoffmann, C., Harrison, C. F., Hilbi, H. (2014) The natural alternative: protozoa as cellular models for Legionella infection. Cell Microbiol 16: 15-26

Hornef, M.W., Pabst, O. (2016) Real friends: Faecalibacterium prausnitzii supports mucosal immune homeostasis. Gut 65: 365-367

Hornef, M.W., Fulde, M. (2014) Ontogeny of intestinal epithelial innate immune responses. Front Immunol. 5: 474

Ingmundson, A., Alano, P., Matuschewski, K., Silvestrini, F. (2014) Feeling at home from arrival to departure: Protein export and host cell remodelling during Plasmodium liver stage and gametocyte maturation. Cell Microbiol 16: 324-333

Jacobsen, I.D., Wilson, D., Wächtler, B., Brunke, S., Naglik, J.R., Hube, B. (2012) Candida albicans dimorphism as a therapeutic target.  Expert Rev Anti Infect Ther 10: 85-93

Jae, L.T., Raaben, M., Herbert, A.S., Kuehne, A.I., Wirchnianski, A.S., Soh, T.K., Stubbs, S.H., Janssen, H., Damme, M., Saftig, P., Whelan, S.P., Dye, J.M., Brummelkamp, T.R. (2014) Lassa virus entry requires a trigger-induced receptor switch. Science 344: 1506-1510

Jermy, A. (2017) DIARY: Seven days in spring. (A personal account from the Nature Microbiology Chief Editor about his time at the 2nd International Meeting of the SPP 1580).

Jeschke, A., Zehethofer, N., Lindner, B., Krupp, J., Schwudke, D., Haneburger, I., Jovic, M., Backer, J.M., Balla, T., Hilbi, H., Haas, A. (2015) Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis. Proc Natl Acad Sci USA 112: 4636-4641

Jeschke, A., Haas, A. (2018) Sequential actions of phosphatidylinositol phosphates regulate phagosome-lysosome fusion. Mol Biol Cell 29: 452-465

Jacobsen, I.D., Hube, B. (2017) Candida albicans morphology: still in focus. Exp Rev Anti-infect Ther 15: 327-330

Kasper, L., Seider, K., Gerwien F., Allert S., Brunke S., Schwarzmüller T., Ames L., Zubiria Barrera C., Barz D., Mansour M. K., Vyas J. M. , Haas A., Reiling N., Haynes K., Kuchler K., and Hube B. (2014) Identification of Candida glabrata genes involved in pH modulation and modification of the phagosomal environment in macrophages. PLoS One 9: e96015

Kasper, L., König, A., Koenig, P.A., Gresnigt, M.S., Westman, J., Drummond, R.A, Lionakis, M.S., Groß, O., Ruland, J., Naglik, J.R., Hube, B. (2018) The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes. Nature Commun 9: 4260

Kasper, L., Seider, K., Hube, B. (2015) Intracellular survival of Candida glabrata in macrophages: immune evasion and persistence. FEMS Yeast Research, 15: fov042.

Kaufmann, E., Spohr, C., Battenfeld, S., De Paepe, D., Holzhauser, T., Balks, E., Homolka, S., Reiling, N., Gilleron, M., Bastian, M. (2016). BCG vaccination induces robust CD4+ T Cell responses to Mycobacterium tuberculosis complex-specific lipopeptides in guinea pigs. J Immunol 196: 2723-2732

Kissing, S., Hermsen, C., Repnik. U., Nesset, C.K., von Bargen, K., Griffiths, G., Ichihara, A., Lee, B.S., Schwake, M., De Brabander, J., Haas, A., Saftig, P. (2015) Vacuolar ATPase in phagosome-lysosome fusion. J Biol Chem 290: 14166-14180

Kissing, S., Rudnik, S., Damme, M., Lüllmann-Rauch, R., Ichihara, A., Kornak, U., Eskelinen, E.L.,  Jabs, S., Heeren, J., De Brabander,J.K., Haas, A., Saftig, P. (2016) Disruption of the v-H-ATPase complex in liver causes mTORC1-independent accumulation of autophagic vacuoles and lysosomes. Autophagy 13: 670-685

Koch-Edelmann S, Banhart S, Saied EM, Rose L, Aeberhard L, Laue M, Doellinger J, Arenz C, Heuer D. (2017) The cellular ceramide transport protein CERT promotes Chlamydia psittaci infection and controls bacterial sphingolipid uptake. Cell Microbiol doi: 10.1111/cmi.12752. „Editor's Choice“ in October 2017

Kolbe, K., Möckl, L., Sohst, V., Brandenburg, J., Engel, R., Malm, S., Bräuchle, C., Holst, O., Lindhorst, T.K., Reiling, N. (2017). Azido Pentoses: A new tool to efficiently label Mycobacterium tuberculosis clinical isolates. Chembiochem 18: 1172-1176

Kolonko, M., Geffken, A.C., Blumer, T., Hagens, K., Schaible, U.E., Hagedorn, M. (2014) WASH-driven actin polymerization is required for efficient mycobacterial phagosome maturation arrest. Cell Microbiol 16: 232-246

Kraft, S., Jouvin, M.-H., N. Kulkarni, Kissing, S., Morgan, E.S., Dvorak, A.M., Schröder, B., Saftig, P. and Kinet, J.-P. (2013) The tetraspanin CD63 is required for efficient IgE-mediated mast cell degranulation and anaphylaxis. J Immunol 191: 2871-2878

Kuhlmann, N., Wroblowski, S., Knyphausen, P., de Boor, S., Brenig, J., Zienert, A.Y., Meyer-Teschendorf, K., Praefcke, G.J., Nolte, H., Krüger, M., Schacherl, M., Baumann, U., James, L.C., Chin, J.W., Lammers, M. (2016) Structural and Mechanistic Insights into the Regulation of the Fundamental Rho Regulator RhoGDIα by Lysine Acetylation. J Biol Chem 291: 5484-5499

Külzer, S., Charnaud, S., Dagan, T., Riedel, J., Mandal, P., Pesce, E.R., Blatch, G.L., Crabb, B.S., Gilson, P.R., Przyborski, J.M. (2012) Plasmodium falciparum-encoded exported hsp70/hsp40 chaperone/co-chaperone complexes within the host erythrocyte. Cell Microbiol. 14: 1784-1795

Külzer, S., Petersen, W., Baser, A., Mandel, K., Przyborski, J.M. (2013) Use of self-assembling GFP to determine protein topology and compartmentalisation in the Plasmodium falciparum-infected erythrocyte. Mol Biochem Parasitol 187: 87-90

Lampe, E.O., Brenz, Y., Herrmann, L., Repnik, U., Griffiths, G., Zingmark, C., Sjöstedt, A., Winther-Larsen, H.C., Hagedorn, M. (2015) Dissection of Francisella-Host Cell Interactions in Dictyostelium discoideum. Appl Environ Microbiol 82: 1586-1598

Lang, C., Rastew, E., Hermes, B., Siegbrecht, E., Ahrends, R., Banerji, S., Flieger, A. (2012) Zinc metalloproteinase ProA directly activates Legionella pneumophila PlaC glycerophospholipid:cholesterol acyltransferase. J Biol Chem 287: 23464-23478.

Lerner, T.R., de Souza Carvalho-Wodarz, C., Repnik, U., Russell, M.R., Borel, S., Diedrich, C.R., Rohde, M., Wainwright, H., Collinson, L.M., Wilkinson, R.J., Griffiths, G., Gutierrez, M.G. (2016) Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis. J Clin Invest 126: 1093-1108

Lerner, T.R., Queval, C.J., Fearns, A., Repnik, U., Griffiths, G., Gutierrez, M.G. (2018) Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells. BMC Biol 16: 1

Liss V, AL Swart, A Kehl, N Hermanns, Y Zhang, D Chikkaballi, N Böhles, J Deiwick and M Hensel (2017) Salmonella enterica Remodels the Host Cell Endosomal System for Efficient Intravacuolar Nutrition. Cell Host Microbe 12:390-402. "Paper of the Month" (April 2017) of the German Society for Microbiology and Hygiene (DGHM).

Liss V, Hensel M (2015) Take the tube: remodelling of the endosomal system by intracellular Salmonella enterica. Cell Microbiol 17: 639-647

Lührmann, A., Newton, H.J., Bonazzi, M. (2017) Beginning to understand the role of the type IV secretion system effector proteins in Coxiella burnetii pathogenesis. Curr Top Microbiol Immunol 413: 243-268

Mayer, F.L., Wilson, D., Jacobsen, I.D., Miramón, P., Slesiona, S., Bohovych, I.M., Brown, A.J., Hube, B. (2012) Small but crucial: the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans. PLoS One. 7: e38584

Mayer, F.L., Wilson, D., Hube, B. (2013) Hsp21 potentiates antifungal drug tolerance in Candida albicans. PLoS One 8: e60417

Mayer, F.L., Wilson, D., Hube, B. (2013) Candida albicans pathogenicity mechanisms. Virulence 4: 119-128

Mehlitz, A., Karunakaran, K., Herweg, J.A., Krohne, G., van de Linde, S., Rieck, E., Sauer, M., Rudel, T. (2014) The chlamydial organism Simkania negevensis forms ER vacuole contact sites and inhibits ER-stress. Cell Microbiol 16: 1224-1243

Mesén-Ramírez, P., Reinsch, F., Blancke Soares, A., Bergmann, B., Ullrich, A.K., Tenzer, S., Spielmann, T. (2016) Stable translocation intermediates jam global protein export in Plasmodium falciparum parasites and link the PTEX component EXP2 with translocation activity. PLoS Pathog 12: e1005618

Michelucci, A., Cordes, T., Ghelfi, J., Pailot, A., Reiling, N., Goldmann, O., Binz, T., Wegner, A., Tallam, A., Rausell, A., Buttini, M., Linster, C.L., Medina, E., Balling, R., Hiller, K. (2013). Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production. Proc Natl Acad Sci USA 110: 7820-7825

Miramón, P., Kasper, L., Hube, B. (2013) Thriving within the host: Candida spp. interactions with phagocytic cells. Med Microbiol Immunol 202: 183-195

Moyes, D.L., Wilson, D., Richardson, J.P., Mogavero, S., Tang, S.X., Wernecke, J., Höfs, S., Gratacap, R.L., Robbins, J., Runglall, M., Murciano, C., Blagojevic, M., Thavaraj, S., Förster, T.M., Hebecker, B., Kasper, L., Vizcay, G., Iancu, S.I., Kichik, N., Häder, A., Kurzai, O., Luo, T., Krüger, T., Kniemeyer, O., Cota, E., Bader, O., Wheeler, R.T., Gutsmann, T., Hube, B. (co-corresponding author), Naglik, J.R. (2016) Candidalysin is a fungal peptide toxin critical for mucosal infection. Nature 532: 64-68. This paper which was selected "Paper of the Month" (April 2016) of the German Society for Microbiology and Hygiene (DGHM).

Müller, S., Faulhaber, A., Sieber, C., Pfeifer, D., Hochberg, T., Gansz, M., Dauth, S., Brix, K., Saftig, P., Peters, C., Henneke P., Reinheckel, T. (2013) The endolysosomal cycsteine cathepsins L and K are involved in macrophage-mediated clearance of Staphylococcus aureus and the concomitant cytokine induction. FASEB J 28: 162-175

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